Big Health
App-Based Cognitive Behavioral Therapy for Insomnia/Anxiety
Big Health is developing a suite of apps that deliver cognitive behavioral therapy for certain mental health conditions without the need for patients to make clinical visits. The company has developed Sleepio for insomnia and Daylight for generalized anxiety disorder; both apps have been proven to work in controlled trials and have generated more data in sleep-focused clinical trials than drugs like Valium or Ambien. The company has also pioneered a novel revenue model for these services.
Cognoa
Digital Diagnostics and Therapeutics for Autism
For autistic children, the earlier a diagnosis is made, the more effective the intervention. However, demand for pediatric neurologists is so high that many children wait more than a year to be evaluated.
Cognoa is developing a digital test that leverages machine learning and AI to analyze video of a child in question and return a diagnosis to the parent. They are also developing a digital therapeutic for children on the autistic spectrum.
Both programs have received FDA breakthrough status, and Cognoa has submitted the diagnostic for regulatory approval.
Ieso Digital Health
Building the first AI Therapists
Ieso is the UK’s leading digital therapy provider in the space of mental health and has developed the first and only outcomes-linked mental health treatment dataset in existence. By leveraging this dataset across multiple indications (anxiety, stress, depression, PTSD), the company aims to develop next-generation mental health tools driven entirely by artificial intelligence. The company has completed early feasibility work around these AI tools and is now preparing to enter clinical development in several indications.
MedRhythms
Music as Medicine
MedRhythms is a digital therapeutics company that uses sensors, music, and software to build evidence-based, neurologic interventions to affect a variety of conditions. The company leverages the ability of music to directly stimulate the brain, resulting in neurological entrainment across the organ. Follow-on indications include multiple sclerosis, Parkinson’s Disease, acute stroke, and Alzheimer’s Disease.
MedRhythms has received a Breakthrough Device Designation for its lead program in chronic stroke recovery, and has almost completed enrollment in a pivotal clinical trial.
Resilience Lab
Resilience Lab is the largest community of clinicians working collaboratively to produced better outcomes and to improve access to quality mental health services. Resilience Lab operates a telemedicine-enabled practice that includes a diverse team of best-in-class therapists and is committed to delivering the best care experience. Resilience Lab is powered by innovative technology allowing clinicians to deliver care remotely and automates all non-clinical work to foster therapeutic alliance and team-based care.
Clinicians are trained at the Resilience Institute, an online platform for modern mental health practitioners that offers continuous learning and training to deliver holistic, evidence-based and affordable care.
Suvera
Reinventing Tools for Chronic Care Management
Suvera is a digital health platform that connect GPs to their patients with long-term conditions. By consistently monitoring patients’ vitals, medications, and symptoms over time, it empowers GPs to provide high-quality care to patients when they need it, and not just according to a schedule.
Suvera is developing machine learning algorithms that monitor patient trends, enabling earlier interventions in the patient’s disease course.